Basic Fibroblast Growth Factor, also known as bFGF or FGF2, is a member of the fibroblast growth factor family. This growth factor plays a significant role in promoting cell differentiation and proliferation. It also is a highly potent catalyst of DNA synthesis in a variety of cell types from mesoderm and neuroectoderm lineages.
Recombinant BioBov bovine FGF2 and CBD-FGF2 (FGF2 fused to a cellulose binding domain) are produced in N. tabacum leaves.
Recombinant BioBov FGF2 and CBD-FGF2 are comparable to a commercially available, highly purified (>95%) counterpart, as determined by a cell-proliferation assay in 3T3 fibroblast cells.